It’s not unusual for amphibians to be able to regenerate, but axolotls take it to the next level. On top of being able to regenerate limbs, the animal can also rebuild their jaws, spines, and even brains without any scarring. Professor Stephane Roy of University of Montreal explained to Scientific American:
You can cut the spinal cord, crush it, remove a segment, and it will regenerate. You can cut the limbs at any level—the wrist, the elbow, the upper arm—and it will regenerate, and it’s perfect. There is nothing missing, there’s no scarring on the skin at the site of amputation, every tissue is replaced. They can regenerate the same limb 50, 60, 100 times. And every time: perfect.
Scientists have also transplanted organs from one axolotl to another successfully.
They are critically endangered in their natural setting
As a result of habitat loss, pollution, and the introduction of invasive species like tilapia and carp, these salamanders are being pushed closer and closer to extinction.
In an attempt to revive the species, researchers have built “shelters” made from reeds and rocks to filter the water and create a more desirable living space. Unfortunately, the numbers continue to decline. There were about 6000 wild axolotls documented in a 1998 survey, but today, researchers are lucky to find any. For a brief amount of time in 2014, biologists failed to find a single water dog, and feared the salamanders had gone extinct in the wild. Luckily, some have since been found roaming the water. And although it’s not ideal, even if the elusive animal disappears from the wild entirely, the species continues to thrive in captivity.
Science is looking to harness that ability
The Salk Institute for Biological Studies is studying how regeneration works in animals like axolotls, and released two studies in 2012 with their findings. The hope is that if we can fully understand regeneration, we can recreate the phenomenon in human beings.
Unfortunately, results so far have shown that the process might be even more complicated than expected. The scientists worry that humans might not even have the necessary genes to successfully regenerate. But there’s a silver lining: While regrowing limbs might not be on the table, future studies can shed some light on smaller healing techniques.
“It is important to understand how regeneration works at a molecular level in a vertebrate that can regenerate as a first step,” said the studies’ senior author, Tony Hunter. “What we learn may eventually lead to new methods for treating human conditions, such as wound healing and regeneration of simple tissues.”